Trifluoroacetic acid is produced in the reaction; how should the material of the equipment be chosen?
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Trifluoroacetic acid is produced in this reaction. Glass bottles are used in the laboratory, and now scaling up the process to an industrial scale is planned. What material would be suitable for the reactor? Hastelloy or stainless steel lined with PTFE?
For stainless steel lined with PTFE, feel free to contact me; I’m happy to discuss any related questions.
It depends on the operating temperature of your reactor: if it is below 100°C, a PTFE lining is used, while if it is above 100°C, the ETFE (F40) coating method can be employed.
For the heat exchange section, pressure-free sintered silicon carbide is recommended; feel free to contact me if needed.
There are several key factors to consider: your synthesis process, the corrosivity of the raw materials and by-products, moisture levels, the presence of fluoride ions, as well as temperature and pressure. Just trifluoroacetic acid alone is not sufficient to determine the appropriate material to use.