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\"Five Pairs\" Management of Chemical Reagents

2025-09-08View Original

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I. What is “five-pair” management? According to GB 18265-2000 \"Requirements and Technical Specifications for the Opening of Hazardous Chemicals Business Enterprises\", the \"five doubles\" management system refers to: double verification, double storage, double dispatch, double locks, and two sets of records. II. Which chemicals require \"five doubles\" management? 1. Requirements for the handling of highly toxic chemicals: Implement a comprehensive “double-control” system. Basis: Article 7 of the Measures for the Administration of Licenses for the Operation of Hazardous Chemicals stipulates that: “When applying to operate highly toxic chemicals, in addition to meeting the conditions specified in Article 6 of these measures, it is also necessary to establish systems such as double-person verification, double-person storage, double-person dispatch, dual locks, and two sets of records for such chemicals.” "2. Requirements for the management of drug-related controlled substances: “Four-pair” management (two persons for locking, two persons for acceptance, two persons for verification). Basis: Article 31 of the Measures for the Management of Drug-Related Controlled Substances states that: “Special warehouses shall be equipped with anti-theft facilities, and special cabinets shall use safes.” ; Dedicated warehouses and counters shall be managed under a dual-person, dual-lock system. For pharmaceuticals and other chemicals that can be used to manufacture drugs illegally, double verification is required for inventory entry, and double checking is necessary for inventory release, to ensure that the records match the actual items on hand. "3. Requirements for the management of easily exploitable explosives: “Two-person” management (two people responsible for receiving and issuing, and two people responsible for storage). Basis: Article 30 of the “Measures for the Public Security Management of Easily Exploitable Explosives” stipulates that “Easily exploitable explosives deemed to be major hazard sources must be stored separately in dedicated warehouses, with a system in place where two people are responsible for receiving and issuing them, and two people are responsible for their storage.” "4. Requirements for the handling of chemicals that can be used to manufacture drugs: There are no explicit “five-pair” management requirements. Basis: Article 9 of the Regulations on the Management of Chemicals That Can Be Used to Manufacture Drugs stipulates that: “Those applying to operate with chemicals of Category 1 that can be used to manufacture drugs must have storage facilities that meet **technical standards.” "III. Recommendations for management practices: Hierarchical and categorized management – Develop differentiated management strategies based on the properties of chemicals and regulatory requirements. Clear labeling – Clearly label chemicals with different management requirements to avoid confusion regarding the applicable standards. Staff training – Ensure that managers accurately understand and implement the relevant management systems. Complete records – Maintain accurate and complete records, and conduct regular checks to align records with actual conditions. Regular inspections – Establish an internal inspection mechanism to identify and correct issues in management in a timely manner. Only highly toxic chemicals truly require full implementation of the “five doubles” management system ; Controlled drugs and chemicals used in drug production are subject to the \"four doubles\" management system ; For hazardous chemicals that are easy to explode, a \"two-person handling and two-person storage\" management system must be implemented for major hazard sources ; However, there are no clear “five doubles” management requirements for precursor chemicals. Companies should implement appropriate management systems based on the specific categories of chemicals and regulatory requirements, in order to ensure compliance while avoiding waste of resources. Properly understanding and implementing these regulations is of great significance for passing safety inspections and ensuring safe production in enterprises.

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