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To date, the organic sulfur hydrolysis catalyst developed independently by the Qilu Petrochemical Research Institute has been in stable operation for over 300 days at Sinopec Puguang Natural Gas Purification Plant, replacing imported catalysts, and for over 200 days at Yuanba Natural Gas Purification Plant; its overall performance matches that of similar catalysts available abroad. Sinopec Puguang Gas Field is the origin of the **\"Gas Transmission from Sichuan to the East\" project, and its gas purification plant has an annual processing capacity of 12 billion cubic meters. The natural gas from this gas field contains a high level of organic sulfur; therefore, it is necessary to first convert this organic sulfur into hydrogen sulfide, and then remove the hydrogen sulfide through absorption by amine solution, thereby completing the purification process. In 2012, the research institute developed a specialized organic sulfur hydrolysis catalyst for natural gas, which passed the evaluation conducted by the Science and Technology Department of Sinopec; the comprehensive performance of this catalyst is on par with that of similar catalysts used abroad. At that time, the imported catalysts used in the Puguang purification plant had not yet reached the end of their useful life, so domestic organic sulfur hydrolysis catalysts had to remain unused. In September 2013, the Puguang gas field served as the first site to utilize domestically produced catalysts; the industrial-scale tests of the sulfur production and hydrogenation catalysts developed by the research institute were successful from the very first attempt, providing support for the use of domestic catalysts. On May 14, 2020, a meeting to advance the industrial application experiments of natural gas organic sulfur hydrolysis catalysts was held at the Dazhou facility. Departments and units such as the Science and Technology Department of Sinopec and Qilu Petrochemical have overcome the impact of the pandemic by using video conferences to communicate and work together to advance the localization of catalysts. At the end of 2020, with the support of the Technology Department at the headquarters, the project team at the research institute took advantage of the maintenance period at the Puguang gas field to apply the hydrolysis catalyst they had developed independently to the hydrolysis unit there. After application, both the physicochemical properties of the catalyst and its performance in industrial applications reach the level of similar catalysts abroad.