How should I design a laboratory-scale process for a 50-kilogram scale?

Pilot experiment design is quite troublesome; you have to figure it out on your own

I’m not sure about your material situation, so it’s hard to say. The heat released by your material is equal to the amount absorbed by your cold medium. Coils can be placed inside the pot.

First, you should clarify the primary purpose of building this set of devices. Hehe. This laboratory-scale process is still intended to collect data for large-scale production; it’s equivalent to a small pilot plant. Right? This is the foundation of plant design; therefore, when designing a plant, you should start from this point and consider whether the pilot plant designed can reflect the conditions of future large-scale production plants. There are also 50L reactors available for pilot testing that are made of glass; the imported ones generally have better quality. If you have sufficient funds, it’s worth considering them, as this allows for a clear view of the reactions taking place inside. Pipe design is also based on the conditions of production. It should be clear that the diameter of seamless steel pipes refers to the outer diameter, and there are also differences between thick-walled and thin-walled pipes, so be sure not to get it wrong. Hehe. If there are no issues such as high viscosity or solid materials that can cause blockages, and the flow rate is not high either, then a pipe diameter of around 10 mm should be sufficient ； If any of the above situations apply, then each specific issue will be considered individually. As for the heat exchange area, it can be roughly estimated based on the temperature changes of the medium and its volume; this information can be found in standard process design manuals, so I won’t go into further detail. It is important to keep in mind that the purpose of your experimental design is to accumulate data and experience for large-scale production.

50 kilograms isn’t much. Do you plan to operate continuously or intermittently? If it’s continuous, the measurement equipment needs to keep up; if it’s intermittent, it’s much simpler. As long as there is appropriate temperature and pressure control, that’s basically sufficient. Due to their small diameter, pipes can be made of glass hoses, PVC, tetrafluoroethylene, rubber hoses, etc.

I think this post should be posted in the industrial design section

I think this post should be placed here, as the production capacity is too low and I’m not familiar with the process design section. It belongs to the pilot-scale category, so precise calculations are not necessary; it is widely used in most material analysis laboratories.