12-Aminododecanoic acid synthesis

Is it possible to hydrolyze laurolactam?

I am doing my graduation project and want to have a detailed plan that can be applied to industrial production. . . . . . I can't find any information now. . . Very depressed. . .

I accidentally saw this and thought of it. I don’t know if there is a way to prepare 6-aminocaproic acid.: Derived from the hydrolysis of caprolactam. Add caprolactam, concentrated hydrochloric acid and 3 times the amount of distilled water into the reaction tank, stir, raise the temperature and reflux for 1.5 hours, and control the temperature to 103-106°C. After the reaction is completed, the measured conversion rate should be above 95%. Add distilled water to dilute to 10% concentration to obtain 10% 6-aminocaproic acid hydrolyzate. Flow the hydrolyzate evenly into the ion exchange column at a flow rate of 5-10L per hour for adsorption. After the flow is finished, close the outlet and soak overnight. Wash the ion exchange column with distilled water and remove the hydrochloric acid (check the effluent to ensure there is no chloride ions). Then, flow 3.5% ammonium hydroxide evenly at a flow rate of 5-10L per hour. After the flow is finished, close the outlet and soak overnight. After continuing to finish ammonium hydroxide the next day, flow into distilled water for elution, and collect the eluate containing 6-aminocaproic acid. Add activated carbon to decolorize, filter, and concentrate the filtrate under reduced pressure at 47-70°C to nearly dryness. Add ethanol while hot and stir to precipitate crystals. After cooling, shake off and filter to obtain the crude product. Dissolve the crude product in distilled water, add activated carbon and decolorize at 60°C for 1 hour. Strain while hot. The filtrate was concentrated under reduced pressure to nearly dryness. Add ethanol to precipitate crystals, cool and filter, wash the crystals with ethanol and dry to obtain 6-aminocaproic acid. The overall yield of caprolactam is 75-80%.

Omega-dodecanolactam. Colorless crystals. Melting point 153℃. Slightly soluble in water. Easily soluble in organic solvents such as ethanol, ether, and chloroform. Polymerization occurs when heated. Used to make nylon-12, etc. It is formed by trimerizing butadiene into 1,5,9-dodecatriene, which is then epoxidized, hydrogenated, and rearranged into dodecane, and then oximated and rearranged.