Leakage at the chromatography injection port
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Hello everyone! I have a simple question for you. What are the signs of air leakage at the chromatography injection port? And how should it be dealt with once leakage is detected? Thank you! This post was last edited by Canghai Yili Sha on 2009-2-11 at 16:17
I recommend that you take a look at the special thread launched by the moderator for exchanging experiences and discussions on gas chromatography applications
The most typical phenomenon is that the integrated data becomes smaller； Solution: One is that the sealing head is loose; tighten it ； Second, if it’s damaged or has holes, just replace the pad ； This is considered a consumable item.
From the workstation perspective, if there is a leak, the baseline drifts. Just replace the gasket at the injection port; it’s likely that too many injections have been made, causing leaks
Baseline drift \Regular noise \Retention time variation \Decreased peak area
The most typical symptom is a decrease in the peak height compared to before, and replacing the gasket will solve the problem
What was said above is quite good; to add one more thing, if there is severe air leakage, it can be felt at the injection port, and a sound will also be heard – in that case, simply replace the gasket.
The direct consequence of air leakage during import is lower analysis results. Check whether the air cushions at each interface are in good condition, and then perform a leak test using soapy water after passing the carrier gas.
It can be heard; moreover, almost no peak appears after another injection. If the two injections are made close to each other and the peak from the second injection is significantly smaller, it is likely due to air leakage. Tighten the air inlet with a wrench, and if that doesn’t work, replace the gasket. This post was last edited by limingshuguang on 2009-2-14 at 12:53