On the synthesis of **phenols
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Catalytic hydrogenation method: The best raw material is ***; production and consumption situation
p-Aminophenol was synthesized using p-hydroxyphenol as the starting material, Raney nickel as a catalyst, and hydrazine hydrate for reduction, with the optimal reaction conditions investigated in order to provide reliable data for industrial production. The optimal process conditions for the reaction are: a molar ratio of n(p-cresol):n(hydrazine hydrate) of 1:2, 10 g/mol of Raney nickel, a reaction temperature of 77.5°C, and a reaction time of 3 hours. The yield of the product can reach 82.3%, with a purity of 98.5%. http://www.cheminfo.gov.cn/05/UI/ScinTech/Show.aspx?tblName=hgwz&xh=497896 This is the address of the paper; the original poster can take a look at it!
We should start with p-nitrochlorobenzene! ! ! Hydrolysis followed by reduction is a simpler approach to use. However, the added value of such products is relatively low; therefore, large production volumes are necessary – at least 10,000 tons per year is required to make a profit, otherwise it’s not worthwhile! ! !
The profit margin on *** phenol is definitely not as good as that of ***. We plan to go with direct hydrogenation reduction for *** anyway, but thanks anyway to the person who posted above
It seems that Shijiazhuang Coking has been using ***direct hydrogenation reduction for some time; it’s believed to be a technology developed by Hebei University of Technology. It’s not clear whether this approach was successful or not. Those who are aware of this situation could please provide some information
Currently, there are studies on the direct hydrogenation of ammonia to produce ammonia. Companies such as Anhui Bayi Chemical and Jiangsu Yangnong Group are involved in this area, but these two companies have already filed patents. The liquid-phase continuous hydrogenation reactor is a patent owned by a company based in Hangzhou; the CEO of this company presented a technical paper on continuous hydrogenation at last year’s Modern Chemicals conference. However, this technology is not yet mature, and it seems that the company mentioned above has not started commercial production yet.
***Direct hydrogenation reduction, with Raney nickel as the catalyst
It’s a good article, but it doesn’t explain the specific process clearly