Who knows the detection limit of chromatography?
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Who knows the detection limit of chromatography? ppm or lower? Compared to mass spectrometry, which one has a lower detection limit?
The types being analyzed are not the same; how can they be compared? Liquid chromatography and gas chromatography are used to determine content, while mass spectrometry is used to analyze the constituent elements
In simple terms, the detection limit of chromatography is the lowest concentration that can be accurately measured by chromatography. There are hundreds of detectors available for chromatography, with dozens of them being commonly used. In terms of the lowest detectable concentration alone, ECD, PID, HID, and DID can all achieve levels in the PPB range, while most detectors have detectable concentrations in the PPM range or up to the macroscopic level. Therefore, when compared based on the minimum detection limit, the two cannot be compared. When we first came into contact with mass spectrometry, chromatography was used for quantification while mass spectrometry was used for qualitative analysis. Each of the two has its own emphasis. Personal opinion. This post was last edited by chengjingbao on 2009-3-4 22:22]
Chromatography is a separation technique, and its detection limit depends on the performance of the detector used in chromatography; detectors such as PFPD, ECD, and DID can achieve detection limits in the ppb range. Mass spectrometry is also a commonly used detector for chromatography, such as the common GC-MS and HPLC-MS.
Be more specific – we are learning *these topics, and maybe I can look into them properly.