What industrial equipment is suitable to replace the rotary evaporator?
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A company provides a synthesis process in which a rotary evaporator is used for concentration. The required production capacity is one ton per day. The rotary evaporator is obviously not suitable for an industrial project of this scale. What industrial equipment is suitable to replace the rotary evaporator? This post was last edited by brainandrain on 2009-3-9 13:51 ]
The method of boiling in a large pot is more suitable, unless it is not possible.
I dare to say that the organic solvent methylene chloride is boiled in a large pot
Using falling film or rising film evaporators, the resistance is reduced and the evaporation efficiency is high. It is especially suitable for vacuum evaporation of heat-sensitive materials.
It is recommended to use the distillation method. I guess the temperature of the evaporator you use should not exceed 40°C. The boiling point of methylene chloride is 40°C. If negative pressure is used, the boiling point should be lower. If you mainly collect methylene chloride, it is recommended to use this method, followed by a condenser for collection. It is not recommended to use a vacuum evaporator because the boiling point of methylene chloride is lower than the boiling point of water. This post was last edited by tongle on 2009-3-10 15:48 ]
I think you can try a falling film or rising film evaporator.
I checked the data of methylene chloride and found that if evaporation is used for concentration, the methylene chloride must be evaporated first, and a condenser needs to be used to collect the gaseous methylene chloride. We can take advantage of the fact that the melting point of methylene chloride is lower than that of water. Is it feasible to use the method of crystallizing water at low temperatures? The density of methylene chloride is higher than that of water and the melting point is lower than that of water. The poster can consider it.
Is it better to be more conservative and use a large tank to heat methylene chloride and add 2 condensers? Will the efficiency be very slow?
The reaction kettle is desolvated, most of the dichloromethane is evaporated under normal pressure, water is put into the receiving tank to seal, and the frozen brine is condensed. After evaporating most of the solvent, vacuum the remaining methylene chloride directly from the kettle. The recovery rate is 80%. Industrial experience
When collecting alcohol from traditional Chinese medicine, you can replace the rotary evaporator with a spherical concentration pot, right?
Thin film evaporators are commonly used in industry to concentrate or remove solvents under vacuum conditions.
Methods short-path distillation, sub-boiling distillation, molecular distillation, equipment Baidu search a lot