Methods for drying organic substances
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There is a organic compound with a purity of around 90%; this compound sublimes easily at around 100 degrees Celsius. I’m thinking of using a desiccant to absorb the moisture present in it and to measure the amount of water absorbed. Could you recommend any suitable desiccants? Or there are other ways to determine the moisture content in it
The original poster is too vague; the properties of such organic substances should be specified, right? Solid? Liquid? There is no need to raise the drying temperature to the boiling point of water; drying at 70-80 degrees for a longer period yields the same results. Looking forward to the original poster’s additional information
What was said upstairs is correct; you didn’t clarify whether it’s a liquid or a solid. Solids are difficult to dry using desiccants – only liquids can be dried in this way. If sublimation is a concern due to high temperatures, low-temperature vacuum drying can be used, with a buffer system in place to capture any substances that might sublimate; generally, there are no problems with this approach.
Silica gel can be used; place the sample that needs to be dried along with silica gel in a sealed container and leave it there for a few days. Solid sodium carbonate can also be added, as it absorbs moisture as well
This organic compound is solid at 100 degrees Celsius, and it sublimes after melting
You could try low-temperature vacuum drying.
Is no desiccant needed for low-temperature vacuum drying?
In our laboratory, for organic substances that are in solid or powdered form, we place them in a vacuum oven and dry them under vacuum at low temperatures (the temperature ranges from room temperature to a value determined by the properties of the substance). To measure the amount of water, a fresh desiccant is placed in the drying flask located at the outlet of the vacuum oven; after drying, the weight is measured. For example, polylactic acid powder is dried at around 40 degrees for one night. If the liquid itself is volatile (indicating a low polarity), extraction can be used: a solvent that is soluble in water or your target product is selected, and after separation of the layers, the desired substance is obtained. Although this method may not be precise, it serves as a quick initial dehydration technique. If you really want to find specific methods, it’s best to provide details such as physical properties.
We also need to consider the volume of processing. If it’s only for use in the laboratory and the amount is small, then use an oven with a lower temperature setting. If the quantity is large, vacuum drying is used in production.
You use vacuum drying, and phosphorus pentoxide is placed at the bottom during drying