Chlorine toxicity analysis
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This post was last edited by sunjl1981 on 2013-1-6 at 19:51. Dear seniors, I have just started working on chlorine-related research. Could anyone provide some specific information on the toxicity analysis of chlorine? It would be better if it’s not something that can be found on Baidu; I’m looking for professional knowledge. Thank you in advance~ # ， ， &
Study the physicochemical properties and toxicity mechanisms of chlorine?
To be precise, it is the influence of physical and chemical properties on toxicity, or the mechanism by which physical and chemical properties give rise to the toxicity of chlorine gas
It should refer to the physical and chemical properties of chlorine; there is plenty of information on this topic in forums. It is also included in the production safety precautions.
Chlorine is hydrolyzed into hydrochloric acid and hypochlorous acid; hydrochloric acid damages the alveoli or bronchi, in a manner similar to phosgene, but its toxicity is several hundred times lower. Cl2+H2O --> HCl + HClO. O || Cl-C-Cl + H2O --> 2HCl + CO2. Phosgene reacts readily with water, which may explain its higher toxicity – even just a few PPM per minute can cause damage to the respiratory system. These are my personal opinions; although I work with these substances, I still feel that I’m not proficient enough in this area. Please correct me if I’m wrong; thank you
Physical and chemical properties: Appearance and characteristics: Yellow-green liquefied gas with an irritating odor. Melting point (°C): -101. Relative density (air = 1): 2.48. Boiling point (°C): -34.5. Relative density (water = 1): 1.47. Saturated vapor pressure (Kpa): 506.62 (10.3°C). Critical pressure: 7.71 (Mpa). Critical temperature (°C): 144. Solubility: Highly soluble in water and alkaline solutions. Main uses: Bleaching, production of chlorine compounds, hydrochloric acid, polyvinyl chloride, etc. Toxicological data: Acute poisoning: LD50: LC50: 850 ppm, 1 hour (inhalation in rats). Subacute and chronic toxicity: In rabbits, inhalation of 2–5 mg/m³ for 5 hours per day over 1–9 months resulted in weight loss, upper respiratory tract inflammation, pneumonia, pleurisy, and emphysema. Rats exposed to 41–97 mg/m³ by inhalation, 1–2 hours per day for 3–4 weeks, developed severe but non-lethal emphysema and tracheal lesions. Mutagenicity: Cytogenetic analysis: human lymphocytes at 20 ppm. Sperm morphology analysis: Mice administered orally at 20 mg/kg for 5 days (consecutively). Ecological information: This substance poses serious threats to the environment; special attention should be paid to pollution of water bodies, as well as to fish and other animals.