The issue of stationary phase loss in gas chromatography-mass spectrometry analysis
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In gas chromatography-mass spectrometry analysis, why is the issue of stationary phase loss given particular attention? How to reduce stationary phase loss?
http://www.chem.agilent.com/zh-CN/Support/FAQs/GC/Hardware/General/Pages/KB001427.aspx 1. The column temperature should not be too high; it should lie between the lowest and highest operating temperatures of the stationary phase. 2. The flow rate of the carrier gas should not be too high. Attention also needs to be paid to the sample: its pH value should not be that of a strong acid or a strong base. For gas chromatography, the sample should preferably not contain inorganic salts, as these can affect the lifespan of the column.