Synthesis methods of salicyl chloride
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I’m seeking help from everyone: what are the methods for synthesizing salicyl chloride, and which one is the best? ! ! Urgent need
Synthesized from salicylic acid and thionyl chloride
Phosgene synthesis was also used in the past. But that thing is too toxic; it’s probably been phased out by now. Thionyl chloride is a commonly used chlorinating agent; the friend mentioned above is correct. Generally, thionyl chloride reacts at around 60 degrees Celsius under reflux cooling conditions.