Hydrolysis products of epichlorohydrin under acidic conditions
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What are the hydrolysis products of epichlorohydrin under acidic conditions?
1. The main product of the hydrolysis of epichlorohydrin under alkaline conditions is glycidol, and the reaction mechanism involves nucleophilic substitution. The hydrolysis conditions have a significant impact on the degree of hydrolysis; as the molar ratio of water in the reactants increases, the reaction temperature rises, and the reaction time lengthens, the degree of hydrolysis increases significantly. When the molar ratio of epichlorohydrin to water is 1:7, the reaction temperature is 98°C, and the reaction time is 2 hours, the degree of hydrolysis reaches a maximum value of 99.6%.
Hydrolysis products under acidic conditions: MCH (3-chloro-1,2-propanediol) is the main product, with GLD (glycidol) as a secondary product (which further hydrolyzes to GLC, glycerol); 1,3DCH (1,3-dichloro-2-propanol) is present in smaller amounts. Under acidic conditions with chloride ions present, MCH is the main product, 1,3DCH is a secondary product, and GLD is present in smaller amounts (it further hydrolyzes to MCH). MCH is quite stable.