Gas chromatographic analysis of o-aminop-henol
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Hello, dear teachers. I would like to ask if anyone has experience with the gas chromatographic analysis of o-aminop-henols and o-nitro-p-henols All the analyses I consulted were done using liquid chromatography. I wonder if FID can be used for analysis in gas chromatography, and what kind of column should be used. Thank you!
This component has low volatility and poor thermal stability at higher temperatures; it is recommended to use high-performance liquid chromatography for analysis. If gas chromatography must be used for analysis, it is likely necessary to carry out a derivatization reaction to obtain more volatile derivatives before analysis. Since numerous sources indicate that liquid chromatography is commonly used for analysis, why do you choose gas chromatography for this purpose? Add some more challenging elements to your analysis work?
Both amino and phenolic hydroxyl groups are prone to degradation; therefore, the liquid phase should also be an acidic one