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What is Dingtongoxime? Is dingtongoxime toxic?

2018-08-06View Original

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What is Dingtongoxime? Butyl oxime is also known as 2-butyl oxime ; **same oxime ; Alpha and beta oxime; Molecular formula: C4H9NO; Molecular weight: 87.12; Boiling point: 72; Property description: Colorless oily liquid. Melting point: -29.5; Boiling point: 152–153.59–60°C (at 2 kPa); Relative density: 0.9232 (at 20/4°C); Refractive index: 1.4410. Can react with alcohols ; Miscible with ethers, soluble in 10 parts of water. Production method: It is obtained by the reaction of butanone with hydroxylamine hydrochloride. It can also be obtained by the reaction of butyl oxime with hydroxylamine sulfate. Uses: Mainly used as an anti-caking agent in alkyd resin coatings and a silicon curing agent. This product is used as an antioxidant to prevent caking, compared to butyraldoxime ; **Oximes are effective. Is Dintoxim toxic? Health hazards: It is irritating to the eyes, nose, throat, and mucous membranes. Prolonged exposure can cause dermatitis. This product is often used in combination with 2-hexyl, which can exacerbate the peripheral neuropathy caused by 2-hexyl; however, no peripheral neuropathy was observed when butenoxime was used alone. Toxicity: It belongs to the low-toxicity category. Acute toxicity: LD50 3400 mg/kg (oral, rats) ; 6480 mg/kg (rabbit dermal) ; LC50 23520 mg/m3, 8 hours (rat inhalation) ; When inhaled at 30 g/m3, it causes a strong odor and irritation ; When inhaled at 1 g/m3, it causes mild irritation. Irritation: In rabbits, when applied to the eyes, 80 mg causes irritation. Rabbit percutaneous open irritation test: 13780 μg (24 hours), mild irritation. Mutagenicity: Sex chromosome deletion and nondisjunction: 33,800 ppm in brewer’s yeast. Reproductive toxicity: Minimum toxic concentration for inhalation in rats (TCL0): 3000 ppm (for 7 hours), during days 6–15 of pregnancy; it causes abnormalities in the development of the craniofacial region (including the nose and tongue), as well as abnormalities in the development of the urogenital system, and leads to coagulation disorders. Hazardous properties: Flammable; its vapors can form explosive mixtures with air. In contact with open flames, high temperatures, or oxidizers, it poses a risk of fire and explosion. Its vapor is heavier than air, allowing it to spread over considerable distances at lower levels; it can catch fire and reignite when exposed to an open flame.
Reply #22018-08-11
Based on GBZ230-2010, it is definitely toxic; all substances are classified as having some degree of hazard, and there is no category for non-toxic substances. The toxicity of this substance is likely quite high.
Reply #32018-08-13
You can tell whether a substance is toxic or not just by looking at its molecular formula. For organic compounds, there are many isomers with the same molecular formula but different structures, as well as impurities such as --CN and --NO
Reply #42021-05-10
The most advanced production method currently used for the synthesis of butyl oxime is the ammonia oximation method.

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