The water removal issue in the imidazoline synthesis process
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This post was last edited by yygntqti on 2019-4-22 at 11:36. In the process of synthesizing imidazolines using organic acids and diethylenetriamine, the presence of water as a by-product significantly slows down the reaction. Currently, water ring vacuum pumps are used in production for vacuuming and water removal, but the results are rather poor; after a reaction at 200°C for 20 hours, about 0.3% of water remains, resulting in an unsatisfactory level of reaction completion. As an expert in this field, do you have any suggestions?
It is necessary to clarify the reaction mechanism; it is not clear whether water accelerates or hinders the reaction rate.
There are many methods for water removal; it is essential to understand the reaction mechanism as well as the properties of the raw materials and products
There is a reaction with a similar structure in which acetic anhydride is used as a dehydrating agent; it is said to also act as a catalyst. Additionally, for ring closure, trying to use a base might work.
:You can choose a few different times to measure the conversion rate; it’s likely that the reaction slows down over time, as your acid is already quite weak