Seven-stage model of chemical engineering technology from concept to industrialization--Table of contents (updated in real time)

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This post was last edited by xiouxingzhe on 2026-7-20 09:43. The seven-stage model of chemical technology from idea to industrialization (Issue 100) —— General table of contents (updated in real time). Dear friends: For your convenience, here is a link to the compiled table of contents, which will be updated in real time as uploads progress. (The link is problematic; only issue 22 is valid.) Section, Issue Number, Title, Main Content: Introduction and Overview, Issue 1: The origin and overall structure of the seven-stage model – The topic was introduced by a question from a young engineer ； Overview of the seven-stage model ； Schedule for Issue 100: Part 2 – The uniqueness of chemical technology innovation, why this framework is needed, an overview of investments and risks at various stages; three key characteristics: long validation cycles, high investment requirements, and systematic risks ； Three major industry problems ； Input-Risk Curve Analysis Phase 1: Inspiration-Driven Phase 3 – The essence of inspiration: it isn’t something that comes about passively; it arises from collisions, stemming from encounters rather than mere imagination ； The four locations where the collisions occurred ； When inspiration strikes, record it first without judgment. One of the entry points for Issue 4 – observing unexpected outcomes in experiments: use experiment expectation cards to establish clear expectations ； Stay vigilant to any abnormalities throughout the entire process ； Record first, then ask questions ； Penicillin and Teflon cases: Part 5, the second source of inspiration – theoretical reasoning, which involves making “if… then…” deductions based on existing theories ； Three Questions for Reasoning ； Coupling of the two principles ； Rapid Elimination Using the First Principles of Thermodynamics, Issue 6: Inspiration Entry 3 – Two Ways of Reading Literature: Searching for Results vs. Understanding the Ideas ； Deliberate practice of active association ； Functional retrieval method ； Patent search isn’t just about checking whether someone has already done it. Part 4 of Issue 7: Sources of Inspiration – Identifying industry pain points; the complaints of frontline workers hide real issues ； Translate complaints into challenges ； Ask Five Whys, Episode 8: Insights #5 – Transferring Technologies Across Fields: Technology Libraries Beyond the Chemical Industry ； Three-step method for functional search ； Transplantation is about recreating principles rather than copying them ； Microreactor Cases, Issue 9: The Creative Pool – A Place to Store Inspiration. What is a creative pool? ； Three-label system ； Review the monthly practice exercises on a weekly basis. Issue 10: MVR cases – Seeing possibilities in challenges. The origins of MVR technology: from the problem of high steam costs to cross-disciplinary exploration. From understanding the principles of MVR to theoretical analysis to verify its feasibility. Phase 2: The birth of innovation. Issue 11: Keeping unviable approaches out of the laboratory at the lowest cost, and conducting screenings before massive investment is made ； It takes more courage to be willing to give up than to be willing to invest ； Sunk Cost Fallacy, Issue 12: Defining Issues in Scientific Conceptual Argumentation – Turning Vague Ideas into Verifiable Scientific Questions ； Construct a complete logical chain for scientific hypotheses ； Conduct desktop simulations first ； Patent Search, Issue 13: Assessing the Size of the Market for Business Concept Validation ； Competitive landscape assessment ； Can the accounts be balanced? ； What to do when scientific and business conclusions differ? Issue 14: Quadrant Decision-Making – Go or No-Go: Approaches for the double-high/double-low/single-high quadrants ； The importance of documenting decision-making – Common pitfalls in issue 15: reluctance to give up, perfunctory reasoning, conducting reasoning only on one side; the sunk cost fallacy ； Arguing for show is more dangerous than not arguing at all ； Ignore policy risks ； Taking “it might work” as “it will definitely work”: Case study of the 16th PPS project – a decision-making process that led to approval for a project of “double high” standards. The scientific and commercial evaluations sowie the comprehensive decision-making process involved in expanding such a project from a scale of thousands of tons to tens of thousands of tons. Reflections on the preliminary decisions regarding the Shenhua Dow Yulin coal chemical project: A project worth hundreds of millions that underwent nine changes in its design over ten years, before ultimately being abandoned ； Lessons from changes in the market environment, rising investment levels, and tightening environmental constraints. Conclusion of Phase 2 of Issue 18 – Two cases, one set of principles; five core principles for Phase 2 ； Relationship to subsequent stages: Phase 3: Technology development. Issue 19 – Moving from “chemistry” to “chemical engineering”; the same chemical equation behaves very differently at different scales ； Data Faith ； Key decision points ； Broadly defined, pilot testing includes both pilot trials and industrial-scale tests. The 20th concept validation experiment – first answer the question of “whether it’s possible”; minimalist principles for experimental design ； Repeating it three times to confirm is not by chance ； Stop losses promptly when it’s not feasible. Issue 21: Catalyst and Material Selection – The tripartite balance of performance, lifespan, and cost; Principles for compiling candidate lists ； Activity and selectivity must be considered together ； Preliminary stability assessment ； Cost assessment covers the full scope; Issue 22: Optimization of reaction conditions – identifying the operational window rather than conducting a single-factor scan to determine key variables ； Sensitivity scanning to find the operating window ； Boundary condition testing ； The trap of premature optimization