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The research and practice of accident prevention and control (abbreviated as “prevention and control”; for simplicity, this term will be used consistently hereafter) first require methodological guidance, and the development of specific methods for accident prevention and control also depends on methodology. As is well known, many methods for accident prevention and control have been proposed in response to accidents. At present, although there are countless specific methods for accident prevention and control, they have not yet reached the level of a systematic methodology. Clearly, by summarizing the existing specific methods for accident prevention and control, a methodology for such prevention and control can be derived. Through analysis and synthesis, I have summarized the methodologies for accident prevention and control into roughly 7 types, namely the intrinsic safety method, the key control method, the early warning identification method, the limited safety method, the multiple protection method, the management efficiency method, and the systematic control method. My personal insights are limited; fellow sea lovers, please keep adding more information. First, the concept of intrinsic safety was first developed in the fields of aviation and mechanical safety abroad. It holds that, in terms of reliability, humans are far inferior to machines. Therefore, to achieve production safety, there must be some kind of device that can ensure the safety of people and equipment even in the event of human error – that is, a safety protection device or a safety system – so as to make the equipment itself \"inherently safe\". Since then, the intrinsically safe design approach has been extended to many areas. In summary, the specific approaches to implementing intrinsically safe design involve two aspects: reducing the probability of accidents (such as improving equipment reliability, using reliable process technologies, installing error-prevention devices, and enhancing the system’s resilience to disasters), and reducing the severity of accidents (such as limiting energy flow or dispersing risks, preventing the release of energy, and installing buffering devices). However, sometimes intrinsically safe methods require substantial funding and high-tech investment, resulting in high implementation costs. Furthermore, the intrinsically safe approach cannot prevent the emergence of new safety issues; how can this be considered intrinsically safe? Therefore, in terms of scientific rigor, the term “inherently safe” can only be understood in a synonymous sense. Second, key prevention and control methods: Modern people’s production and daily life are highly complex, with numerous safety issues arising, and there are many aspects that need to be addressed in terms of prevention and control. There have always been differing opinions regarding whether a comprehensive approach or key targeted methods should be used. The currently more common and practical approach is the focused prevention and control method, which involves adjusting the accident prevention and control capabilities according to the importance or severity of the objects to be protected; this is essentially a form of \"dimension reduction\" concept. On a macro level, the whole world, **, and provinces (states, cities) all have specific targets or areas that require focus in accident prevention and control at certain times, usually determined based on the industry or the level of risk associated with the hazard sources ； At the micro level (typically enterprises), comprehensive prevention and control is generally adopted, but different accident prevention measures are also implemented depending on key areas of focus. Third, the precursor identification method holds that as long as signs of an accident are detected in advance, it is possible to take timely actions to prevent the accident. In plain terms, this methodology aims at preventing accidents in the first half of their occurrence. This methodology can determine whether there are signs of an accident by detecting various safety status parameters, and transmit this information to the accident prevention and control system for adjustments, in order to prevent accidents from occurring. Based on this methodology, various techniques have been proposed over time, such as “risk identification techniques,” “safety monitoring techniques,” and even “safety psychophysiological testing techniques” and “safety behavior observation techniques.” Fourth, the limited safety approach holds that \"accidents can occur in any system,\" and that \"by relying on experience and conducting various cost-benefit analyses, it is always possible to find an accident probability that balances the various interests and is accepted by the public.\" In other words, from the perspectives of safety economics and reality, there is no simple inverse relationship between safety investments and the probability of a certain accident occurring. Rather, once safety investments reach a certain level, it becomes very difficult to further reduce the probability of that accident occurring; therefore, we might as well consider this critical value of the accident probability as an acceptable safety indicator. Therefore, in practical operations, safety indicators are often used as the recognized standards to assess the quality of safety performance and whether something is safe. Fifth, multiple protection methods refer to the implementation of various safety safeguards (such as redundancy) to prevent accidents from occurring. Obviously, the probability of an accident is related to the number of safety protections in place and the probability of an accident occurring with each such protection. Sixth, the management effectiveness approach holds that through safety management, human-caused accidents can be effectively prevented and controlled. Management effectiveness methods aim to control people’s unsafe behaviors, that is, they use education, enforcement, and culture as means to prevent accidents. Clearly, this is a more macroscopic and comprehensive methodology for preventing human-caused accidents, but it tends to overlook engineering as an important means of accident prevention. Seventh, the systematic prevention and control method is a methodology for accident prevention and control that has been developed on the basis of the academic ideas and working methods of systems theory and cybernetics. Due to the systematic and complex nature of safety issues, some key methods from systems theory and cybernetics are widely applied in accident prevention and control. Practice has shown that these methods are highly effective, and they are among the most favored approaches for such purposes. Areas such as functional analysis of safety systems, risk identification, assessment, and control, behavioral safety management, optimization of human-machine interaction systems, safety strategies based on the “3E+C” framework (engineering, education, enforcement, and culture), and prediction of safety performance all make extensive use of the concepts and methods provided by systems theory and cybernetics, thereby helping to elevate the level of accident prevention and control. In summary, the aforementioned 7 methodologies for preventing and controlling accidents are not independent of one another; rather, they are interconnected and even overlap in some areas. In the actual process of accident prevention and control, we should focus on selecting the most suitable methods or combining them; only in this way can better results be achieved in accident prevention and control.