How to test the content and composition of dimethyl formate? How can we ensure its purity?

This post was last edited by chicanpk on 2018-2-26 09:27. A document was found on Xiaomucichong for your reference. Analysis method for dimethyl formate 1. Instrument: High-performance liquid chromatograph 2. Chromatography column: 205mm×4.6mm (i.d.) stainless steel column filled with Kromasil C18 5um packing 3. Operating conditions: Mobile phase – Methanol:Water = 70:30; Wavelength – 230nm; Flow rate – 1.0 ml/min; Column temperature – Room temperature; Retention time – 5.02 minutes. The above parameters can be adjusted appropriately according to the characteristics of the instrument. 4. Determination 4.1 Weigh 50 mg of the standard substance and place it in a 25 ml volumetric flask; dilute with methanol and mix well. After complete dissolution, inject the sample ； 4.2 Weigh 50 mg of the standard sample and place it in a 25 ml volumetric flask; dilute with methanol, mix well, and inject after complete dissolution ； 4.3 Calculation: Percentage content = (A2 × m1 × P) / (A1 × m2). Where: A1, A2 represent the peak areas of the standard sample and the sample respectively; m1, m2 represent the masses of the standard sample and the sample respectively; P represents the content in the standard sample