Problems with fluorination during the diazotization of aniline-based fluoroboronic acids to form salts: 01 Agglomeration of precipitates
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This post was last edited by Desert Fish on 2016-1-26 at 11:17. I have been working on the diazotization of aniline derivatives using fluoroboric acid, followed by salt hydrolysis and fluorination, and I have a few questions for everyone. 1. I read that amines can be dissolved in solvents and then salts or acids can be added to form salts. My amine has a high melting point; after dissolving it in toluene, I added 15–18% salt acid at a temperature of over 60 degrees Celsius. A yellowish-white substance began to precipitate. After adding more of this solution, the temperature was raised slightly, to around 80 degrees Celsius, and the precipitate gradually formed clumps, eventually turning into large lumps. Is it because the temperature is too high? But does low temperature lead to incomplete salt formation?
There are too many questions; it is recommended to ask them one by one in separate posts to facilitate in-depth discussion
Do we need to raise the issue of the same experiment separately? I think it’s better to discuss them together; if they’re separated, there isn’t much connection between them
The temperature can’t be too high; I have done something similar to this before.