Can solvent A in Karl Fischer reagent be replaced with methanol?
Thread Content
In moisture analysis, there is one bottle of A solvent 16 containing Karl Fischer reagent, while methanol is available in packs of 3 bottles each; the main component of A is methanol. After conducting multiple experiments, it was found that the titration volumes achieved using A and methanol are similar. Can methanol be used as a substitute for A solvent?
This post was last edited by qugd on 2023-12-12 09:22. In principle, it is possible, but the solvents used in Kjeldahl titration are usually strictly dehydrated. Since you are using commercially available methanol, its water content may be quite high, which would result in excessive consumption of Kjeldahl reagent. Of course, this is another matter if you have strictly dehydrated the methanol you are using.