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Building on the previous background regarding the activation of irradiation corrosion products, the current applications of this technology are focused on nuclear industry safety management and specific industrial inspection areas. The main applications include: in nuclear power plant radiation safety management, by studying the formation and migration patterns of activated corrosion products, various source calculation software tools such as ACE, Pactole, and STAP have been developed to quantitatively assess the radiation fields in the primary loop. These tools support shielding design and personnel dose management, thereby reducing the radiation risks associated with shutdowns for maintenance. The optimization guidance for primary loop water chemistry involves adjusting the operating parameters of the primary loop based on activation mechanisms; for example, optimizing the pH value of the pressurized water reactor’s primary loop to 7.4 and controlling lithium levels can reduce the deposition and activation of corrosion products containing nickel and cobalt, alleviate axial power imbalance issues, and enhance the operational safety of the plant. The thin-layer activation corrosion monitoring technology relies on the thin-layer activation (TLA) technique developed based on the principle of radiation activation. It can be used for online corrosion monitoring in industrial settings such as oil pipelines, enabling accurate detection of the corrosion rate of equipment and ensuring the operational reliability during the transport of highly corrosive media. The assessment of the safe disposal of nuclear waste focuses on the hydrogen generation resulting from anaerobic corrosion of carbon steel under irradiation conditions in deep geological disposal repositories, evaluating the impact of long-term hydrogen accumulation on the safety of the repository’s sealing barriers, thereby providing a basis for the long-term safety evaluation of the geological disposal of high-level radioactive waste.