Seeking help with Aspen Adsorption simulation for the chromatography process of traditional Chinese medicine extracts, including the elution and separation of components

Thread Content

Seeking help with Aspen Adsorption simulation for the chromatography process of traditional Chinese medicine extracts, including the elution and separation of components. Creating a simulation of the liquid chromatography process for traditional Chinese medicine is a dynamic process that involves the adsorption and elution of liquid components. First, an aqueous solution containing the components is introduced, then the flow is stopped; pure water is then added to achieve equilibrium, and finally, ethanol is used for elution. It should be possible to do this. Based on the information found online and by following the official procedures for ethanol dehydration, it’s not possible to carry out the process. First, there is abnormal decomposition, and initialization fails; then there are errors in the solver, which are likely due to issues with the process parameters. But trying all possible parameters doesn’t work either. I’m asking for any methods or advice from those with experience – even if it involves payment