Organic reaction equations
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I have a question for everyone: How is the organic reaction equation written for the synthesis of anisole by reacting dimethyl carbonate (DMC) with phenol? What are the side reactions besides the main reaction? Those who know it, please write it down. Thank you!
This post was last edited by qugd on 2024-4-19 09:45. Phenol is equivalent to an aryl alcohol; when dimethyl carbonate reacts with phenol, anisole is formed through the hydrolysis of the ester, under the action of an appropriate catalyst. Using dimethyl carbonate as a methylation reagent allows for the avoidance of the highly toxic dimethyl sulfate; it is an environmentally friendly methylation reagent. Currently, solid basic catalysts are used; the resulting carbonic acid is removed from the reaction system in the form of carbonates, after which the catalyst is regenerated and returned to the reaction system. This reaction equation is relatively simple: CH3O-CO-OCH3 + 2C6H5-OH ---- catalyst ----> H2CO3 + 2 C6H5-O-CH3. In this reaction, the carbonic acid that is formed exists in the form of carbonates, which are then removed from the reaction mixture.
Some say that phenol and dimethyl carbonate may also form \"diphenyl carbonate\". Those who are aware please write down the reaction equation.
Will diphenyl carbonate be formed? What is the reaction equation? :):)