Common frustrating operations in organic synthesis

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1. While climbing the plate, I forgot to remove the TLC plate until the solvent reached the top. 　　2. Forget the weight of the weighing flask. 　　3. When separating the liquids, I forgot to close the stopcock of the separatory funnel in time; when I looked back, nothing was left. 　　4. The product was lost while passing through the column. 　　5. The pillars have dried out. 　　6. During rotary evaporation, the flask containing the product is submerged in the water bath. 　　7. Forgot to turn on the vacuum while performing rotary evaporation… 8. Continuous boiling occurred during rotary evaporation. 　　9. Pour the reaction mixture into a separatory funnel with a removable stopper. 　　10. The stirrer was taken to the separatory funnel along with the reaction solution, and as a result the stirrer damaged the separatory funnel. 　　11. When performing NMR, only a deuterated solvent was used; I forgot to add... 　　12. Believing that one has a good memory, failing to label multiple samples only to regret it the next day. 　　13. Forgot to turn on the circulating water. 　　14. Ensure that the solvent is absolutely pure and completely anhydrous. 　　15. It was only when it was time to carry out the reaction that it was discovered that one substrate was missing. 　　16. Wrong material was added during feeding. 　　17. Failure to verify the raw materials before feeding them in. 　　18. During the material feeding process, it was found that the reaction flask was too small. 　　19. During the quenching reaction, it was found that the reaction flask was too small. 　　20. The bottle was broken during sampling. 　　21. When calculating the feed ratio, the content of the raw materials was not taken into account. 　　22. A decimal point was misplaced when calculating the material ratio. 　　23. Believe that an unreliable reaction can work miracles. 　　24. When separating the layers, discard the product layer. 　　25. The stirrer breaks the bottle. 　　26. To obtain the product, the bottle has to be broken. 　　27. The reaction flask is slid into the oil bath. 　　28. Multi-component parallel tests confused the batch numbers. 　　29. During the overnight reaction, the circulating water pipe fell off the condenser. 　　30. Break the bottle while washing it. 　　31. Conduct reactions with gas release in a closed system. 　　32. During extraction, the live and dead cells do not separate into layers. 　　33. I sneezed while cutting the sodium block. 　　34. Opened the fridge and forgot to close it ； I took the reagent out of the fridge and forgot to put it back. 　　35. Someone else takes your weighed bottles. 　　36. Temperature control failure. 　　37. Shot. 　　38. Boiling over during vacuum distillation. 　　39. Using ether, I keep dozing off. 　　40. While you’re surfing, someone secretly turns your board around. 　　41. During vacuum distillation, it suddenly tripped and pulled back.