Determination of hydroxyl groups in bisphenol A compounds
Thread Content
There are existing bisphenol A phenols and other mixtures; phenol, bisphenol A, and other bisphenol-type compounds with two or three hydroxyl groups are known. I would like to measure the hydroxyl value content in them. May I ask…
The acidity of phenolic hydroxyl groups allows for the determination of their hydroxyl value through acid-base titration in organic basic solvents under non-aqueous conditions. This method lacks significant selectivity, but it requires the use of pH or potential to indicate the endpoint, or special indicators for this purpose. As standard bases, potassium hydroxide or tetrabutylammonium hydroxide can be used. It's just personal advice, not verified by professional sources.
Bisphenol A is generally analyzed using liquid chromatography, and all these components can be separated. To determine the hydroxyl value, it is generally done by acetylation to form carboxylic acids; relevant literature can be consulted for details.
This post was last edited by qugd on 2022-11-18 09:54. Chromatography is used to determine composition, but users may not accept such a method for determining hydroxyl values; acetylation presents issues related to conversion rates, as well as differences in the reactivity of hydroxyl groups depending on their substitution position. The hydroxyl value is generally determined by volumetric methods; near-infrared spectroscopy can also be used, but an appropriate spectral analysis model must be developed for that purpose.