1. Ion exchange resins contain a certain amount of water, and should not be stored outdoors. They need to be kept moist during storage and transportation to prevent drying out, which could cause the resin to break. If the resin dries out during storage, it should first be soaked in concentrated saltwater (10%), after which the concentration should be gradually reduced; it must not be placed directly in water, as this could cause the resin to expand rapidly and break. 2. During storage and transportation in winter, it should be kept in an environment with a temperature of 5–40°C, to avoid conditions that are too cold or too hot, as this could affect its quality. If no insulation equipment is available in winter, the resin can be stored in saltwater; the concentration of the saltwater can be adjusted according to the temperature. 3. Industrial products of ion exchange resins often contain small amounts of low polymers and monomers that have not participated in the reaction, as well as inorganic impurities such as iron, lead, and copper. When the resin comes into contact with water, acids, bases, or other solutions, these substances dissolve into the solution, affecting the quality of the output water. Therefore, new resins must be pre-treated before use: first, the resin is fully expanded using water, and then the inorganic impurities (mainly iron compounds) can be removed using a 4-5% dilute acid solution, while organic impurities can be removed using a 2-4% dilute sodium hydroxide solution. The washing should continue until the solution reaches a near-neutral pH. If used in pharmaceutical preparation, it must be soaked in ethanol. 4. When in use, resins should be kept away from contact with metals such as iron and copper, oils, organic molecules, microorganisms, and strong oxidizing agents, to prevent a decrease in their ion-exchange capacity or even the loss of their functional capabilities. Therefore, it is necessary to carry out periodic activation treatments on the resins depending on the circumstances. The method of activation can be determined based on the level of contamination and the existing conditions. Generally, cationic resins are prone to contamination by Fe during softening processes; they can be soaked in a salt-acid solution and then gradually diluted. Anionic resins are susceptible to organic contamination and can be soaked or rinsed in a mixed solution of 10% NaCl and 2–5% NaOH; if necessary, they can also be soaked in a 1% hydrogen peroxide solution for a few minutes. Other methods include alternating acid and alkali treatments, bleaching, alcohol treatment, and various sterilization techniques. 5. Pretreatment of new resins: Industrial products of ion exchange resins often contain small amounts of oligomers and monomers that have not participated in the reaction, as well as inorganic impurities such as iron, lead, and copper. When the resin comes into contact with water, acids, bases, or other solutions, these substances dissolve into the solution, affecting the quality of the effluent. Therefore, the new resin must be pre-treated before use. Generally, the resin is first expanded with water; thereafter, inorganic impurities (mainly iron compounds) can be removed using a 4-5% dilute salt acid, while organic impurities can be removed with a 2-4% dilute sodium hydroxide solution, until the solution reaches a nearly neutral pH.