Fire separation distance for active pharmaceutical ingredients
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This post was last edited by Grizzly on 2016-11-17 at 17:30. Dear sea friends, I have a question and would appreciate it if you could discuss it and give me some advice. I designed a API factory whose workshops involve the “two key and one major” hazardous reactions of alkylation, nitration, and chlorination. In accordance with the requirements of “two key points and one major requirement”, a fire separation distance of 50,160 must be met. (Actually, we’re a bit wronged; we are active pharmaceutical ingredients, and our level of risk is even lower than that of fine chemicals.) Not to mention the petrochemical industry...) Then, when applying Table 4.2.12 of 50160, it is specified that the fire separation distances required for \"Class A process units\" are 30/25 meters. (The numerator represents petrochemical plants, while the denominator represents refining plants.) ) My facility clearly doesn’t fall under the category of “refining facilities,” but if we use terms like “petrochemical facilities,” we’re going in the wrong direction... I wonder if anyone has encountered such a situation; could you share your experiences?
It is necessary to follow the standard requirements; of course, your items’ grade should be classified in accordance with those standards
A project was carried out without the client’s approval; the design followed the building codes to some extent with slightly reduced spacing, and it could be justified under strict standards as well. Review for the safety section: since methanol is present in the raw materials, the Safety Supervision Bureau requires the use of petrochemical regulations. The boss didn’t know where to go and cry.
Let the client try to use their connections to see if it’s possible to follow the building codes; if that doesn’t work, we’ll prepare a design that complies with petrochemical industry standards, as the client won’t accept anything else – there’s no other option
We’re in the same situation now; fortunately, it’s still in the initial design stage, so there’s time to turn things around.