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Taking into account the background information we have discussed earlier regarding the applicable scenarios, advantages, and disadvantages of various anti-corrosion solutions for heat exchangers, there is no universally \"most effective\" solution. The approach that suits specific operating conditions is the one that yields the best overall results. The optimal solutions for different scenarios are as follows: For environments with neutral conductive media such as seawater or circulating water, a combination of cathodic protection and anti-corrosion coatings is the most effective method; it can cover the entire equipment, compensate for any defects in the coatings, relies on mature technology, and ensures strong stability over long periods of operation. In environments with strongly oxidizing acids such as concentrated sulfuric acid, anodic protection is the most effective solution; it enables a dense passivation layer to form on the metal surface, reducing the corrosion rate to microscopic levels and allowing the lifespan of the equipment to be extended from several months to several years. In extreme corrosion conditions involving strong acids, strong bases, and high salinity: titanium-wound heat exchanger bodies represent the most effective material choice. Titanium resists erosion by the vast majority of highly corrosive substances; moreover, its smooth surface reduces the risk of scaling, and its service life is 5–8 times longer than that of conventional stainless steel heat exchangers. For medium and low temperature conditions with mild corrosion under normal operating conditions, the modified epoxy resin anti-corrosion coating solution is the most effective option: it offers good cost-performance, strong adhesion, and excellent resistance to chemical corrosion, balancing protection effectiveness with cost control. In extreme high-temperature conditions such as waste heat recovery from high-temperature flue gases, the plasma spraying ceramic coating solution is the most effective option – it offers high hardness, resistance to high temperatures and wear, and a service life that far exceeds that of traditional organic coatings, making it suitable for projects that require high reliability. The effectiveness of all solutions depends strictly on the degree of compatibility with the operating conditions; a solution chosen for an inappropriate application not only fails to provide protection but may even accelerate the corrosion and failure of the equipment.