A major breakthrough has been achieved in the key synthesis technology for prochloraz, through collaboration between Yaben Chemical and Su Yuanhai’s research team at Shanghai Jiao Tong University

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Recently, Yaben Chemical, in collaboration with the research team led by Su Yuanhai from Shanghai Jiao Tong University, made a significant breakthrough in the key technology for synthesizing tebuconazole. This innovation involves the use of microreactor technology to upgrade the traditional photobromination process. The relevant results have been granted a **patent license (license announcement number: CN118125941B), and they have also been published in the renowned international journal in the field of chemical engineering, the AIChE Journal (DOI: 10.1002/aic.18693). These achievements provide valuable technical references for the upgrading of processes in the chemical industry in this new area. https://p3-sign.toutiaoimg.com/tos-cn-i-axegupay5k/36f3e1b33089444aa4420949a60449bc~tplv-tt-origin-web:gif.jpeg?_iz=58558&from=article.pc_detail&lk3s=953192f4&x-expires=1766501118&x-signature=d2FgvJiH1wmdiry9SaoblC1yKUM%3D As a new type of fluorine-containing fungicide, the key steps in its synthesis traditionally rely on batch reactors, which suffer from issues such as low efficiency in heat and mass transfer as well as inadequate utilization of light, thereby hindering improvements in the quality and efficiency of production in this industry. The joint research team identified the key pain points in this industry with precision, and utilized microreactor technology to optimize the photobromination reaction process. By developing reaction kinetics models and employing density functional theory (DFT) calculations, they verified the feasibility of the reaction mechanism from both experimental and theoretical perspectives, thereby providing solid scientific support for the practical application of this technology – in line with the new district’s commitment to green and low-carbon industrial development. Lanzhou New Area has always relied on technological innovation to drive industrial development, making every effort to establish platforms for collaborative innovation among industry, academia, and research institutions. It encourages enterprises to deepen their cooperation with top universities and research institutes, and continues to intensify efforts in developing key core technologies. The Project Construction Center of the New Area will continue to strengthen the aggregation of innovation elements. Focusing on key technological fields such as green chemistry and efficient synthesis, it will make every effort to facilitate the transformation and implementation of high-quality technological achievements, swiftly overcome technical bottlenecks hindering industrial development, and effectively support the transition of the chemical industry in the New Area toward greener, low-carbon, and high-end development, thereby laying a solid foundation for the high-quality industrial development of the New Area.