Case Study on the Modification of the Sealed Sampling Valve for Active Pharmaceutical Ingredients in Pesticide Plants

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Dear colleagues and friends, I have recently worked on several projects involving modifications to sealed sampling devices/sampling valves, and I have some insights to share； The user had previously used a faucet-type open sampling method; during inspections, the environmental protection agency found that VOC levels were above the allowed limits, and further testing revealed the presence of Class 1 carcinogens in the medium ； In pesticide factories, the media are at relatively high levels and highly corrosive; lined pipes are commonly used, along with numerous reaction vessels. The modification plan for a sealed sampler that we propose involves installing a pump to create a circulation system, with the sampler placed in this circulation circuit ； At present, there are many problems with sampling devices in domestic fine chemical pesticide factories. The experts from environmental inspection teams have advised that sealed sampling should be adopted, and it is expected that this will become a mandatory requirement in the future. There are also many sampling points in the API factories, with open sampling being the common method; the media involved are often corrosive and toxic. In accordance with the recommendations of the latest environmental inspection teams, it is necessary to switch to closed sampling devices ； The clients contacted are mainly companies in the fine chemicals industry, the BDO industry, the acrylonitrile industry, the polycarbonate industry, and caprolactam factories. Among those dealing with styrene, polyoxymethylene, etc., are companies such as Asahi Chemicals, Lutianhua, Shuguang BDO project, Huasu PVC project, Sinochem’s acrylonitrile project, Zhenhai Refining & Chemical’s acrylonitrile production facility, and Ruiheng’s phenol and propylene projects, among others ； If you have similar concerns, the question is: Could I learn more about imported or domestically produced online sealed sampling valves/samplers/sampling systems that have no dead zones, no residues, help reduce VOC emissions, and work perfectly well with LDAR testing? ； Suitable for liquid sampling: phenol, caprolactam, nylon 66, acrylonitrile, PVC in chlor-alkali plants, paints and coatings, vinyl acetate, BASF specialty chemicals, Yantai Wanhua MDI TDI, ethylene glycol, BDO process liquids, VCM liquids, bisphenol A, etc ； For information requests and technical exchanges, please contact 379662240@qq.com. Thank you very much for your email! Add WeChat 15901919535