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I’m not very familiar with chromatograms... Could you please help?

2016-10-12View Original

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For the chromatogram produced by sample testing, what information do we need to look at when performing distillation? The retention time indicates which component it is, while the peak area represents the amount present. Does a closer retention time mean that the separation is more difficult? Wait
Reply #22016-10-12
This question should be moved to the chemical analysis section. Your basic understanding is correct. Simply put, different components have different peak times (retention times) due to their varying boiling points; those with lower boiling points emerge first, resulting in a shorter retention time. Different components are identified based on retention time, and the peak area represents the content. The closer the retention times are, the closer the boiling points are as well. Since you work in distillation, you should understand that components with similar boiling points are more difficult to separate. Chromatography can be considered as a distillation column, with the order in which peaks appear corresponding to the path from the top to the bottom of the column; it’s just an analogy.
Reply #32016-10-12
May I ask if it is possible to tell whether the two components can be separated well?
Reply #42016-10-13
The simplest method is to compare their boiling points; if the boiling points are similar, separation is difficult, and special columns must be used.

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