Regarding the assessment of acute toxicity?
Thread Content
As is well known, acute toxicity is used to assess pressure pipelines. Now there is a question: Suppose a substance has an acute toxicity value of 1 when ingested, 2 when inhaled, and 3 when absorbed through the skin – how should its acute toxicity be determined? Is it classified as acute toxicity 1?
Based on the information you provided, this substance has different acute toxicity levels depending on the route of exposure. Generally, the acute toxicity level for skin contact of substances is used in the design of pressure pipelines, as this ensures better protection for people’s skin in the event of an accident. Therefore, if this substance is used in the assessment of pressure pipelines, its classification as having acute toxicity level 3 through dermal exposure should be adopted as the criterion. However, if the route of exposure when using this substance differs from the established criteria, please refer to the relevant toxicological data and safety standards, and make a judgment after taking all factors into consideration. .
Based on the on-site conditions, percutaneous and inhalation routes are the most common in such situations. It is very difficult to occur orally. But the guidelines for pressure pipelines don’t specify that assessment should be based on percutaneous or inhalation methods either. There is no source at the moment.
When you have this doubt, you can think back – perhaps your assumption is not valid
Note 1 in GBZ230 states that acute toxicity is determined based on dermal and inhalation exposure