The basic research findings on organosilicon conducted by Zhonglan Chenguang Institute, titled \"A novel silicon-boron reagent facilitating the trans-silicon-borylation of terminal alkynes\", were published in a top international journal

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Research findings on silicone chemistry by China Blue Morning Light Institute published in an international top journal 2025-10-16 Recently, a research achievement resulting from the collaboration between China Blue Morning Light Institute and Nankai University, titled \"A new silicon-boron reagent facilitating the trans-silicon-borylation of terminal alkynes\", was accepted for publication in the internationally renowned academic journal \"German Applied Chemistry\". The publication of this achievement marks significant progress by CLCGI in the field of highly selective synthesis methodologies and the development of fundamental innovation capabilities. \"German Journal of Applied Chemistry\" is one of the most influential top-tier academic journals in the field of chemistry. It is published by the German Chemical Society, and its impact factor in 2024 was 16.1; it is classified as a TOP journal in Category 1 according to the Chinese Academy of Sciences. Renowned for its stringent peer-review standards and pioneering coverage of cutting-edge research, this journal serves as the premier platform for many Nobel Prize-winning chemistry discoveries. In this collaboration, China Blue Morning Light Institute and Nankai University jointly developed a new type of silicon-boron reagent that enables the trans-silicon-borylation of terminal alkynes. This breakthrough overcame the long-standing scientific challenge of achieving high-selective trans-silylation of sterically hindered terminal alkynes, providing a new and effective approach for constructing the scaffolds of pharmacologically active molecules with broad application prospects in the development of innovative drugs.