Noah Fluorine Chemicals: Patent for “A Method for Preparing an Asymmetric Hydrofluoroether” Approved

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Noah Fluorine Chemicals: Patent for “A Method for Preparing Asymmetric Hydrofluoroethers” Approved On March 6, information from the **Intellectual Property Office shows that Zhejiang Noah Fluorine Chemicals Co., Ltd. and Hubei Noah New Materials Technology Co., Ltd. have had their patent for ‘A Method for Preparing Asymmetric Hydrofluoroethers’ approved; the application number is CN121609620A, with the application date being November 2025. The patent abstract states that this invention discloses a method for preparing an asymmetric hydrofluoroether, and it falls within the field of organic fluorine chemistry synthesis. The asymmetric hydrofluoroether in question is 1-methoxyheptafluoropropane. The method involves two consecutive reaction steps: Step S1, in which phosgene and a fluorination catalyst are mixed in an anhydrous, stable solvent under an inert atmosphere until saturation, followed by the slow introduction of tetrafluoroethylene to produce perfluoropropionyl fluoride ； In step S2, the reaction mixture obtained in step S1 is directly fed into a reactor, where it reacts with a methylation reagent and an optional alcoholic additive to produce 1-methoxyheptafluoropropane; the intermediate products are not separated or purified. This invention utilizes the inexpensive raw material tetrafluoroethylene; by optimizing the catalyst combination, solvent system, and process control, it achieves high overall yield and selectivity under mild conditions, with a safe and continuous process suitable for industrial production.